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The variants have both N- and C-terminal nuclear localisation signals (NLSs), but 18 kDa FGF-2 has only C-terminal NLS, and translocation of FGF-2 into the nucleus requires both NLSs, which means transportation of the splicing variants, but not 18 kDa FGF-2, into the nucleus (42)

Thieme R, Pai EF, Schirmer RH, Schulz GE

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Overall, it is recommended that SSRIs be avoided in male patients of childbearing age, whereas their use during IVF appears to be reasonable in women with depression or anxiety disorders ( 3 Effects of SSRIs on embryonic development Exposure to any SSRIs such as citalopram, paroxetine, and sertraline at any time during pregnancy has been shown to increase the risk of fetal mortality (Figure 2) ( postpartum hemorrhage may also be increased

Effects of the KCNQ (Kv7) Channel Opener Ezogabine on Resting-State Functional Connectivity of Striatal Brain Reward Regions, Depression, and Anhedonia in Major Depressive Disorder: Results From a Randomized Controlled Trial

Inflammatory signals