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Prevention of neonatal hyperbilirubinaemia in non-human primates by Zn-protoporphyrin

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IGF-1 LR3 also has reduced binding affinity for IGF-binding proteins (IGFBPs), which normally sequester IGF-1 in circulation and limit its bioavailability

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This step allows the separation of soluble host protein contaminants and recovery of the pellet containing the insoluble ELP fusion protein which is further used on the following step termed cold spin