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Project Orbis TGA has become a partner with the US FDA Oncology Center of Excellence (OCE) Project Orbis initiative since May 2019

Mtb aggregates can feed on the dead macrophages in an ESX-1 and bacterial lipid phthiocerol dimycocerosate (PDIM) dependent manner, without the need for live AMs, thereby avoiding phagocytosis (84).They can further kill other macrophages resulting in a cascade of cell death and inflammation, boosting Mtb transmission

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Harpin induces activation of the Arabidopsis mitogen-activated protein kinase AtMPK4 and AtMPK6

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