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146 TaniguchiC

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We have also shown that the methodology compares favorably to existing methods for thiol clicking and thiol bioconjugation reactions 12,34,35,36,37,38,39,51,52,53

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doi: 10.3389/jpps.2025.15527 Received 02 September 2025 Revised 24 November 2025 Accepted 05 December 2025 Published 16 December 2025 Volume 28 - 2025 Edited by Reza Mehvar, Chapman University, United States Updates Copyright 2025 Kwon, Lee and Kim

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For Jerne this was, as he says, 'remarkable for two reasons: they are present in serum from a normal nonimmunized animal and their number increases enormously within a week after a single injection of a phage-antigen into this animal, i.e., before the serum obtains any appreciable phage-inactivating power' (Jerne, Sept 1955)

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