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10.1038/s41598-024-68061-y 153 TamuraY.FujiwaraY.YamamotoN.NokiharaH.HorinouchiH.KandaS.et al (2015)

Oxidativer Stress frdert die Bildung toxischer Proteinaggregate, wie Beta-Amyloid (bei Alzheimer) und Alpha-Synuclein (bei Parkinson) (7)

As ART alone is insufficient to fully suppress HIV-1 replication, including the transcription and translation of the HIV-1 provirus, there is a critical need to develop new brain-penetrat agents that can effectively target both the CNS and the peripheral immune system to silence HIV-1 and reduce the risk of neuroinflammation