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The study includes adults who are either obese (BMI 30 or above) or overweight (BMI between 27 and 30) and have at least one weight-related health condition alongside moderate-to-severe plaque psoriasis

PI3K/AKT also has many overlapping functions in fibrosis and is found to regulate cell adhesion [133], cell polarity and directional migration [134,135], and actin cytoskeleton dynamics [136]

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Key Goals Improve Circulation and Oxygenation Target: Diabetic neuropathy is commonly associated with impaired circulation in the lower extremities, which can exacerbate symptoms like pain, numbness, and tingling

All data are presented as mean SEM