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Solid organs such as the liver and pancreas are also considered portions of the digestive system

Treatment with febuxostat did not reduce significantly the progression renal disease, with a fall in eGFR in the placebo group of (-0.47 4.48 ml/min/1.73 m2) vs 0.23 5.26 ml/min/1.73 m2 in the febuxostat group

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Alzheimer's trend was not statistically significant, perhaps due to the small number of disease cases

The illness can cause persistent cognitive impairment and brain fog, suggesting chronic brain involvement

8 NUTRITION THERAPY Pancreatic Enzyme Replacement Therapy The majority of patients with CF are on pancreatic enzyme replacement therapy (PERT) with pancrelipase