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Abstract Reactive species produced in the cell during normal cellular metabolism can chemically react with cellular biomolecules such as nucleic acids, proteins, and lipids, thereby causing their oxidative modifications leading to alterations in their compositions and potential damage to their cellular activities

Here, radiolabelled KYNA was provided intragastrally (calculated as ~5 nmol at 20 M), and its appearance in blood, liver and spleen noted, indicating uptake into these organs

Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation

Age-associated nicotinamide adenine dinucleotide decline drives CAR-T cell failure

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