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In vivo study: After treated with LW231 for 42 days in the AAV-HBV mice, the mean declines in HBV DNA was 0.2, 2.2 and 2.3 logs, in HBsAg was 0.3, 0.8, 0.5 logs, in HBeAg was 0.08, 1.1, 0.7 logs comparison to pretreatment levels in mice dosed with 50, 100 and 200 mg/kg LW231, respectively

10.3390/pharmaceutics13101627 48 KlochkovS

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[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Zhang Y, Zhang S, Li B, Luo Y, Gong Y, Jin X, Zhang J, Zhou Y, Zhuo X, Wang Z, Zhao X, Han X, Gao Y, Yu H, Liang D, Zhao S, Sun D, Wang D, Xu W, Qu G, Bo W, Li D, Wu Y, Li Y

WangSGuoSGuoJDuQWuCWuYet alCell death pathways: molecular mechanisms and therapeutic targets for cancer

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