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However, several challenges remain: Patient adherence: Many patients struggle with adherence due to concerns about treatment efficacy ( Limited effectiveness for moderate/severe cases: More effective interventions are needed for moderate to severe psoriasis ( High cost of biologics treatment: The high cost of biologics and the need for long-term treatment limit accessibility Topical treatment limitations: Current topical treatments can have poor safety profiles, high costs, and frequent dosing requirements ( On the other hand, researchers are exploring new avenues to address these challenges

Li X, Le Y, Zhang Z, Nian X, Liu B, Yang X

Oxidative Med Cell Longev 2018:2812904 Hou W, Xie Y, Song X, Sun X, Lotze MT, Zeh HJ 3rd, Kang R, Tang D (2016) Autophagy promotes ferroptosis by degradation of ferritin

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