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Nat Rev Mol Cell Biol 22 (4), 266282 (2021)

doi: 10.3390/toxins15070418 Hernndez-Gil, Javier, Chow, Chun Yuen, Chatras, Hugo, de Souza Frana, Paula Demtrio, Samuels, Zachary V., Cornejo, Mike, King, Glenn F., Lewis, Jason S., Reiner, Thomas and Gonzales, Junior (2023)

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Because symbiont density varied substantially among branches of the same colonies, two tissue biopsies were collected from each colony (labeled AF)one from a branch with high symbiont density (brown in color, termed symbiotic) and another from a low symbiont density branch (pale or white in color, termed aposymbiotic)

The copper component matters significantly for side effects