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Anti-inflammatory prophylaxis of acute gout flares is commonly employed adjunctively in the early phase of treat-to-target ULT, as remodelling of tissue MSU crystal deposits by effective ULT can induce a temporary increase in the frequency of acute gout flares

Nature 596 , 417422 (2021)

Melatonin reduces inflammation and cell death in white matter in the mid-gestation fetal sheep following umbilical cord occlusion

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Andrew: Are these taken in the morning or in the afternoon