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Cancer Cell 35 , 721737.e9 (2019)

High levels of GSTs have consistently been observed in resistant insect strains and play a major role in insecticide resistance [77,98,99]

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To assess whether the senescent phenotype induced by T-DXd was reversible or sustained, we performed washout experiments at different time points: in particular, cells treated with the ADC were allowed to recover in normal growth medium for either 3 or 7 days after the end of treatment