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Clin Drug Investig 35:547558

As an endocrine factor, FGF21 has been shown in preclinical models to exert effects in diverse tissues beyond liver, including adipose tissue, pancreas, skeletal muscle, and the central nervous system

K, L Percentage of apoptosis cell of indicated 769-P (K) and A-498 (L) cells with flow cytometry analysis

While the treatment with NP4 alone caused a strong production of ROS, the preincubation with NAC and subsequent treatment with NP4 showed a poor ROS generation (Fig