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Additionally, in RNAi processes, the 5 nucleobase affects the binding activity of AGOs to siRNA, thus reducing target cleavage activity

We also thank the UT Southwestern Bioinformatics Core for their assistance with ligand docking

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It is worth noting that different transplantation routes (intracardiac injection/intravenous infusion) and mitochondrial sources (autologous/allogeneic) can influence therapeutic outcomes

The newly prepared MEDI7219 (SEQ ID NO:2) tablets containing Tris exhibited a higher bioavailability of 12.4% compared to 5.2% without Tris

column shows the relative scale found by the late acceptance heuristic (Tollenaere et al