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Lachnospiraceae species were more active in the inf_CON group than in the inf_CNCbl40 group, with a notable increase in ribosome-associated inhibitor A/sigma 54 modulation protein, flagellin domain protein, propinyl-CoA carboxylase, and sensor domain-containing phosphodiesterase

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The reprogramming and differentiation processes can introduce genetic mutations or epigenetic abnormalities, this raises concerns about the safety and long-term effects of iPSC-MSCs in clinical applications

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and D.W.J