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26% increase in deaths from cancer

Schebb NH, Khn H, Kahnt AS, Rund KM, ODonnell VB, Flamand N, Peters-Golden M, Jakobsson PJ, Weylandt KH, Rohwer N, et al

This paper highlights the important molecular features of SOD1-ALS, which is not a TDP-43 proteinopathy and may partially explain why treatments evaluated in SOD1 -transgenic mouse models have not generally translated well to the clinic