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Treatment doses for deficiency are substantially higher, typically involving intramuscular injections of 1,000 g or oral supplementation of 502,000 g daily, depending on the underlying cause and severity

Direct measurement of the binding proteins is more informative when available." How should suspected biotin or heterophile-antibody interference change interpretation of an immunoassay-based B12 result

If needed, your provider may recommend lab testing through your primary care physician to explore underlying factors like thyroid function or insulin resistance

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