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Description

NAD+ shortage affects how genes express themselves through reduced sirtuin activity

He Z, Liu J, Liu Y

Avan A, Postma TJ, Ceresa C, Avan A, Cavaletti G, Giovannetti E, et al

Biochim Biophys Acta 1788, 25942602

[Abstract] FEBS Lett

Until today, there are many small molecule blockers of TRPV1 (AZD1386) (Clinical Trials, 2012), TRPA1 (GRC-17536) (Clinical Trials, 2014) and TRPV3 (SAR292833) (Clinical Trials, 2016), apart from topical TRPV1 agonists, such as zucapsaicin (Clinical Trials, 2011) and NGX 4010 (Mou et al., 2014), that have been tested in clinical trials of several NP conditions