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Intriguingly, for those depressed patients with increased baseline inflammation, anti-inflammatory interventions are more likely to improve the response rates [31, 32]

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Tranexamic Acid acts earlier, blocking the signal that instructs melanin production in the first place

In the smoking cessation trial of Prado and colleagues, there was a significant reduction in depression [134], a secondary outcome also seen in the post- traumatic stress disorder trial of Kalivas and colleagues [99]