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J Clin Med Res 2017;9:23347.ArticlePubMedPMC 28

Unfortunately, quality studies that demonstrate the benefits of IV glutathione are based mainly on animal studies since few studies demonstrate its benefits conducted on humans

Another factor involves genes

Both aerobic glycolysis and pyruvate metabolism play important roles in fibroblast proliferation, myofibroblast differentiation, and fibrotic tissue alterations [61, 62]