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10.1021/acs.est.3c01347 82 HerzogI

This directly attenuates the activation of NF-B and STAT3 signaling pathways by these factors, thereby reducing their suppression of insulin-like growth factor-1 function and downregulating ubiquitin-proteasome system-mediated muscle protein degradation (55, 59, 64)

Apocynin was able to restore levels of Collagen 17 and repair damaged skin, leading scientists to believe its possible to reverse our skins timeline at the cellular level