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The hypocretin/orexin neuropeptides are essential for the maintenance of wakefulness and the suppression of REM sleep, and zebrafish possess a functional hcrt-pineal gland circuit, connecting the hcrt and melatonin systems together in sleep consolidation (Appelbaum et al

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doi:10.1007/s00405-016-4301-1

Catalase is a crucial antioxidant enzyme that plays a vital role in protecting cells against oxidative damage 21,22

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