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For another neuraminidase inhibitor, zanamivir (Figure 11a), oral bioavailability is very low due to its polar structure, while its amino acid-coupled acyloxy ester prodrug can be recognized by the luminal cell PepT1 transporter, showing better intestinal membrane permeability and bioavailability

The hepatocellular damage worsens over the first 72 h but may improve spontaneously after that, as a result of regeneration of hepatocytes

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This suggests a link between EGT and conidial health, as has been previously observed 16