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If you want to learn more about dopamine and cognitive performance, read: Dopamine and cognitive performance

Many athletes and fitness enthusiasts get monthly shots to optimize their physical and mental performance

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Important limitation: Neither is FDA-approved, and human clinical data relies heavily on animal models and observational reports

Researchers shared that one 55-year-old woman who struggled with depression and symptoms such as numbness in her feet saw her symptoms gradually lessen within three to four weeks of getting B12 shots

31 Since the 2021 review, one more RCT has been published that compared oral B12 alone, 25 g per day (form not reported), or with folate (800 g per day) versus no supplements for 6 months in patients with mild cognitive impairment