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HK2 inhibits RIPK1 kinase activity through constitutively phosphorylation at serine 32 of RIPK1

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NLRP3 activity has been extensively implicated in the pathophysiology of several metabolic disorders including obesity, type 2 diabetes, gout, and CVD, all of which occur more frequently in BD [82]

Helmy YA, Taha-Abdelaziz K, Hawwas HAEH, Ghosh S, AlKafaas SS, Moawad MM, et al

In contrast, glutamate exposure significantly increased AIF nuclear translocation

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