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If a patient improves rapidly, or conversely, suffers a severe adverse reaction, the presence of multiple unapproved compounds makes it biologically impossible to isolate which specific peptide was responsible for the outcome, rendering the treatment scientifically unmonitorable

Stergiou GS, Palatini P, Modesti PA, Asayama K, Asmar R, Bilo G, et al

The small intestinal barrier in mice is regulated by diurnal variations in the dietmicrobiomeenterocyte MHC-IIIL-10 axis in intraepithelial lymphocytes 10

To overcome the pitfalls of existing clinical immunotherapies, numerous translational studies are concentrating on targeting TAMs in GBM

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A hydrogel based on PEG in the substantial absence of non-PEG polymers is described WO-A 99/14259