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NPT100-18A interacts with the C-terminal domain of -syn, displaces it from the membrane, reducing the formation of -syn oligomers, and subsequently reduced neuronal accumulation of -syn and decreased markers of cell toxicity

However, high TMAO was associated with chronic inflammation and high IL-6 and CRP levels in 179 patients with kidney disease [21]

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[DOI] [Google Scholar] 84.Lien E.J.-C., Lien L.L.-M., Wang R., Wang J