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Oxidative stress has been linked to diseases from cancer to neurodegeneration, among others

Animal care and all experimental procedures were performed in accordance with the Guideline for Animal Experimentation of Nagasaki University with the approval of the Institutional Animal Care and Use Committee (permission number: 1803191437)

doi: 10.1016/j.jdermsci.2023.04.006

It requires careful dosing and endocrine follow-up to avoid ovarian hyperstimulation

At 4 mg weekly, participants lost approximately 17.5% body weight over 48 weeks

Therefore, recovery from stroke likely requires re-mapping lost function onto surviving neural circuitry through structural and functional plasticity [82, 83]