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Although the pathogenic role of oxidative stress in NAFLD pathogenesis is well established (5), there are limited studies available in the literature investigating the potential effect of glutathione supplementation in this condition

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This is in line with higher proportions of HOSC observed in the S-phase of cell cycle during flow cytometry analysis as both CCND2 and CDK6 are important regulators of G1/S phase of cell cycle [44]

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Elevated Egr-1 in human atherosclerotic cells transcriptionally represses the transforming growth factor-beta type II receptor

Overall, L-arginine might have a positive role in the treatment of PD based on current data, and the authors support its use in combination regimen