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Is standard practice to assess tolerance, monitor for adverse events, and identify the minimum effective dose (MED) that produces measurable biological responses without unnecessary exposure

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Vet Ophthalmol 15:6571 Chang RC-C, So K-F (2008) Use of anti-aging herbal medicine, Lycium barbarum , against aging-associated diseases

[DOI] [PMC free article] [PubMed] [Google Scholar] 135.Hine C, Mitchell JR

[Abstract] Biochem Biophys Res Commun

Anecdotally, some users report needing to increase doses over time to maintain effects, which could indicate some degree of desensitization