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A similar level of antioxidant activity (69.460.06%) was observed in callus grown with 8 mg L -1 SiO 2 NPs as well as in presence of Si bulk (69.300.07%)

These are predominantly mild to moderate and transient

The two roles that matter most to a dog's daily health are detoxification and antioxidant regeneration

ROS are a necessary defense system to combat microbial respiratory infections (Lambeth, 2004), but oxidative stress and the excessive production of ROS by numerous cells including monocytes and macrophages, neutrophils, as well as pulmonary endothelial and epithelial cells play a major role in the development of ARDS and its complications during COVID-19 infections (Meftahi et al., 2021)