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The inflammaging process involving the accumulation of pro-inflammatory senescent cells triggers immunosuppressive mechanisms to maintain tissue homeostasis [122]

The iodide salt is polar, but working stocks are typically prepared in DMSO or ethanol, then diluted into aqueous buffers

Additionally, hepatotoxicity is a notable concern, particularly in patients with risk factors such as alcohol consumption, obesity, and diabetes, which can exacerbate liver damage

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However, future research may lead to identification of high-risk DM patient subsets for which malignancy screening may have high value