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The better effect of LCLN than LC was evidenced by the findings of earlier studies 92,100 , likely due to physical attributes (including shape, size, and zeta potential), alongside enhancements in encapsulation efficiency, drug content, drug loading capacity, drug release, and in vitro release of the formulated LC-SLNs, all of which were optimized in the niosomal form 19

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However, the underlying mechanism and effect of L-carnitine on antineoplastic activity of lenvatinib remain unclear

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An emerging body of evidence, including a recent umbrella review, underscores its broader potential in improving metabolic parameters, such as fasting blood glucose and insulin resistance, which are crucial in cardiovascular health (Patio-Cardona et al., 2024)