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Apoptosis, the most common form of PCD, is particularly significant, as granulosa cells apoptosis deprives oocytes of the hormones and survival factors essential for their meiotic and developmental competence, which increases the susceptibility of oocytes to apoptotic factors, ultimately impairing ovarian reserve function

Improves overall skin health: It may help reduce the appearance of wrinkles, fine lines, and dark spots by fighting oxidative stress and improving skin tone

Another layer of regulation of the epigenetic regulatory mechanisms is added through the local production of the metabolites in the nucleus [37]

It is of great theoretical significance and practical value to explore the mechanism of ferroptosis and its role in various diseases and to propose effective and highly targeted therapies

10.1038/nature08817 58 NguyenD

Funding CJ was supported by a Macquarie University Postgraduate Research Scholarship