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It is the first triple-hormone-receptor agonist to reach advanced clinical trials, activating three distinct metabolic pathways that individually would each justify their own drug development program

Two prospective studies of men and women from the Physicians Health Study and Nurses Health Study cohorts found a protective effect of higher PLP blood levels and B6 intakes (from food and supplements) on colorectal cancer risk

This method may also be useful for children or individuals who have trouble swallowing pills

In these locations, it can cause an embolisma blockage that may trigger life-threatening conditions like a stroke or heart attack

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