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[DOI] [PMC free article] [PubMed] [Google Scholar] 167.Michels K.B., Binder A.M

Substantial evidence confirms that gut barrier dysfunction-induced microbial imbalance facilitates bacterial endotoxin (e.g., LPS) translocation across the intestinal epithelium into systemic circulation, precipitating metabolic endotoxemia - a process driving multi-tissue injury through systemic inflammatory responses (Saad et al., 2016)

The metabolic benefits and organ-protective functions of KD are primarily mediated by BHB

The further oxidative activation of carcinogens leads to the development of electrophilic reactive intermediates, which bind to DNA and cause mutation

In: Modern Trends in Human Leukemia IV, 73-76, 1981

As the liver processes mycotoxins and dumps them into the bile, they enter the small intestine