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In a neonatal rat model of hypoxiaischemia, stimulation of the TLR4p38 MAPK signaling pathway induced the production of proinflammatory cytokines, including IL-1, IL-6, and IL-18, while simultaneously downregulating the ferroptosis-related proteins SLC7A11 and GPX4, thereby promoting neuroinflammation and ferroptotic cell death [120]

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Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in diet-induced obese mice

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Stratifying patients on the basis of their degree of autophagy dependence is crucial for clinical translation

Others are trying to replace or avoid traditional growth hormone