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(63) and Lu et al

Choose supplements with high purity, preferably in liposomal or liquid form for better absorption

Lutein primarily works by inhibiting RANKL-dependent osteoclast production, acting on both macrophages and osteoclast precursor cells

Furthermore, calcium stimulates Ca-sensitive K + channel, which results in KCl loss with water that leads to cell shrinkage, and activates calpain, a protease, resulting in cytoskeleton destruction (9,12)