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Q.AhmadW.SiddiquiS.AlamM.et al (2024)

The measurement of TCN2-Cbl provides a more accurate reflection of the vitamin B12 status, particularly in the context of neurological disorders, as it specifically quantifies the fraction of Cbl bound to TCII and available for cellular uptake and metabolism [133]

As a consequence, the higher the intensity of oxidative stress, the lower the motility, live sperm count, and sperm concentration in the semen, as well as the risk of miscarriage and child development abnormalities [2,22,25,63]

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18,19 While PDE-5 inhibitors have revolutionized the management of ED, the remainder of this review will focus on alternative treatment options and potential treatment strategies in the setting of failed PDE-5 inhibitor therapy or contraindications

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