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All participants provided written informed consent before enrollment [1]

Mark each vial clearly with the date of first puncture and the 28-day discard date using permanent marker

Payers do not reimburse based on red blood cell size

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The precise mechanism of hydroxocobalamin's vasoconstrictive effects is unclear, though in vitro studies suggest it acts as a scavenger for NO, binding to it and inhibiting its physiological activity [13]

Even if normal absorption through the intestines is impaired, your body can still absorb a small amount of the vitamin directly through the intestinal lining via passive diffusion