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In transgenic AD mouse models, dietary copper supplementation increased A deposition, -secretase [-site APP cleaving enzyme 1 (BACE1)] expression, neuroinflammation and cognitive deficits

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J Vis Exp 30:2437 Huo C, Jiao L, Li G, Li D, Lin W, Sun Y (2023) HutZ is required for efficient heme utilization and contributes to the pathogenicity of Avibacterium paragallinarum

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The structure of these 2 compounds are shown below

PD-1 can upregulate the expression of PD-L1 in tumor cells and ultimately inhibit the proliferation of T cells and reduce immune function by binding to its ligand PD-L1, thereby facilitating tumor cell immune escape [61,62,63,64], this is the mechanism by which tumor cells evade immune cells with the help of PD-1 in the absence of glutamine