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doi: 10.1016/j.freeradbiomed.2018.12.011 185 LvQNiuHYueLLiuJYangLLiuCet al

Its the patient who feels great at week six and decides to push the dose higher than the protocol calls for without telling me

Hamilton & Hardys Industrial Toxicology

Using HEK-293 adherent cells and K-562 suspension cells treated with varying concentrations of menadione or l-Buthionine Sulfoximine (BSO), two compounds known to affect total glutathione (GSH + GSSG) levels, we assayed the cells in separate assays and in a multiplex assay

CLSM-FLIM CLSM-FLIM imaging was performed on a STELLARIS 8 Leica DMi8 microscope (Leica Microsystems)

Since transcriptional dynamics dependent on NHR-49 appeared specific for genes involved in -oxidation, we hypothesized that defective oxidation of the fatty acids would impair ATP maintenance in the nhr-49(nr2041) mutants