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The signs and symptoms of vitamin B12 deficiency may include: fatigue difficulty thinking and remembering infertility heart palpitations pale skin dementia weight loss numbness and tingling in the hands and feet mood changes constipation a sore tongue low appetite Many people are unclear about precisely what these vitamins do despite vitamin B12 being so important for the bodys healthy function

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It was approved by the U.S Food and Drug Administration (FDA) on December 22, 2025, for chronic weight management

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Because the IOM bases the RDA on the absorbed amount of B12 necessary to prevent deficiency, its straightforward to calculate the IOMs weekly target absorption