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Visible body composition changes reduced body fat (particularly midsection), increased lean muscle tone, improved skin elasticity, and measurable IGF-1 improvements on follow-up blood work

Furthermore, case-reports have associated the use of concentrated green tea-based supplements with liver toxicity in humans 54,55

EASL Clinical Practice Guidelines: drug-induced liver injury

[2] MSM also reduces the production of signaling proteins associated with systemic inflammation, such as interleukin 6 (IL-6) and tumor necrosis factor-alpha (TNF-a)

NMN, but not NR or NAMN, allosterically activated SARM1, with a half-maximal concentration in the low micromolar range [74,75]

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