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CUR-PDT induces ferroptosis of RA-FLS via the Nrf2/xCT/GPX4 pathway to inhibit proliferation in rheumatoid arthritis

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Furthermore, the authors reported that the MCF-7 breast cancer cell line shows an E2-dependent increase in its survival rate, which is abrogated by pre-treating them with the anti-estrogenic compounds ICI-182, 780, or raloxifene (Yu et al., 2012)

Statistical analyses Statistical analysis used a two-sided t-test, with FDR (false discovery rate) correction for multiple comparisons, conducted in Perseus statistical software with default settings

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