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[Google Scholar] Maroto-Snchez, B., Lopez-Torres, O., Valtuea, J., Benito, P

These statins inhibit RhoA/ROCK signaling in penile tissue, thereby increasing the efficacy of sildenafil

Sci Rep 15 , 34806 (2025)

Studies in the PCOSIR rat model demonstrate that metformin reduces ROS levels, resulting in improved mitochondrial function and insulin sensitivity and upregulated PI3K and AKT gene expression (Rabah et al., 2023)