l carnitine with inositol PEAKPURY Ultra Choline, Acetyl-L-Carnitine, & L-Tyrosine – Daily Supplement for Executive Focus & Metabolic Harmony – 150 Capsules : Health & Household PCOS Nutrition Center L-Carnitine (120

The inositol and mental health data isn't as robust as for some of the other benefits, but there is some promising research

The dual agonist mechanism provides robust glycemic control and significant weight reduction, with clinical trials demonstrating A1C reductions of 1.92.4% and weight loss of approximately 1522% of body weight in non-diabetic adults with obesity (SURMOUNT-1 trial), with more modest weight loss typically observed in patients with type 2 diabetes

Nat Rev Drug Discov 20(5):362383 Hajal C et al (2021) Biology and models of the Blood-Brain barrier

However, antiandrogens are not preferred over COCs for hyperandrogenism unless COCs are contraindicated or ineffective (240)

Curr Drug Target CNS Neurol Disord 2002

Cycle Length and Long-Term Use: Initial assessment cycles typically run 12-16 weeks, which aligns with the duration of clinical trials and allows adequate time to evaluate metabolic response and body composition changes