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Pharmacological inhibition of SQOR with STI1 preserved cardiac function and prevented adverse remodeling

This effect may be mediated by the peroxisome proliferator-activated receptor gamma (PPAR)/retinoid X receptor (RXR) pathway, which directly affects gene expression, or by reducing oxidative stress and modifying the inhibitor of kappa B (I-B)/NF-B pathway [75]

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Cytometry .1994;15:9