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The mechanism underlying the favorable effects of L-carnitine on chronic fatigue remain unclear

Patients with ulcerative colitis saw acute flares improve with aloe gel

Trimetazidine was also shown to reduce inflammatory markers in other organs beyond the heart and blood

Thus, this also provides a new paradigm to understand the complex pathological network in OA and offers a theoretical guidance for gut microbiota modulation approaches for the OA prevention or OA therapeutic strategy such as probiotic approach, fecal microbiota transplantation (FMT) or detoxification of certain metabolites

Therefore, abnormalities in MnSOD activity compromise mitochondrial function and lead to disease

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